All the metabolites were found to be excreted to the growth media facilitating product isolation.
Their corresponding metabolites were found to be more cytotoxic, for the same concentration.
At 9 of the 23 sampling points, over 10 plant protection products and metabolites were found.
As a result, 20 important metabolites were found to be significantly altered.
In brain tissue homogenates, ginsenoside Rg1 was detectable and no other ginsenosides or their metabolites were found.
Only a limited number of metabolites were found which was consistent with the existing literature for other phenethylamine-based drugs.
The parent compound as well as several major phase I metabolites were found in rat plasma and brain.Using both in vitro and in vivo methods, we elucidated the metabolic pathway of ZLN005.
Similarly, after administration of 440 2200 mg/day of oral curcuma extract for up to 29 days to patients with advanced colorectal cancer, neither curcumin nor its in vivo metabolites were found in the plasma or urine of the subjects10.
As a result, a total of 19 metabolites (10 phase I metabolites and 9 phase II metabolites) were found and identified.
The intra- and inter-day precisions for TCE metabolites were found to be in the range of 2.37 4.81% and 5.13 7.61%, respectively.
The RapidRIP method was used to quantify the metabolome of seven industrial strains of E. coli revealing significant differences in glycolytic, pentose phosphate, TCA cycle, amino acid, and energy and cofactor metabolites were found.
