Sentence examples for metabolites were enriched from inspiring English sources
The significant metabolites were enriched for pyruvate carboxylase deficiency, cardiogenic shock, non-insulin-dependent diabetes mellitus, and heart failure (Additional File 4: Figure 4Sc).
Non-targeted metabolomics analysis further identified defects in MuRF3−/− hearts where altered metabolites were enriched similarly to those found in pyruvate decarboxylase deficiency, an enzyme with a PPAR-response controlling element [ 54].
For example, pathways for metabolism of terpenoids, polyketides, and other secondary metabolites were enriched among genes born on lineages leading to the common ancestor of Lentisphaerae species and the Chthoniobacter/Methylacidiphilum/Akkermansia/Verrucomicrobium phylogenetic lineage.
The second eluting atropisomers of the HO-PCBs metabolites were enriched in blood and liver; 2,2′,3,3′,6,6′-hexachlorobiphenyl-5-ol in blood was an exception and displayed an enrichment of the first eluting atropisomers.
This was subsequently confirmed by the following bow-tie structure analysis that revealed CPP metabolites were enriched in the giant strong component (see Additional file 2) which was the most connected part in the network.
Similarly to C2, the KEGG term "biosynthesis of secondary metabolites" was enriched with the lowest p value in C3.
An untargeted metabolite fingerprinting analysis of Δ csnE versus the wild type A. nidulans revealed that more than 100 metabolite markers were enriched in the mutant (Nahlik et al. 2010).
Twelve metabolite sets were enriched in HIV patients with NCI compared to HIV-negative controls.
Genes involved in secondary metabolite biosynthesis were enriched in both the up- and down-regulated gene sets.
11 metabolite sets were enriched in the HIV plasma lipidome compared to controls (p<0.05, FDR<5%) including bile acid biosynthesis, steroidogenesis and sulfation, LPC and acylcarnitine biosynthesis, and pathways involved in fatty acid biosynthesis, elongation, oxidation, and metabolism.
Gene Ontology (GO) studies showed that the phenyl propanoid pathway, pigment biosynthesis, polyketide biosynthesis, and other secondary metabolite pathways were enriched in Vagad under control and drought conditions as compared with RAHS-14.
