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The measurement timing had large effects on all measured metabolites except for tryptophan, octadecanoic acid, phosphoric acid and erythritol, which, on average, explained 34.0% of the total phenotypic variation of the measured metabolites.
In general, inoculation of seeds with A. brasilense and by foliar spraying resulted in down-regulation transcription of oxidative stress genes (APX1, APX2, SOD2, SOD4) in roots, but genes were always up-regulated by leaf spray of metabolites, except for APX1.
Profiling analyses of UV-active metabolites in the rice calli and seeds expressing the OASA1D transgene also demonstrated that drastic accumulation of tryptophan had little effects on the profiles of other UV-active metabolites except for the accumulation of a few minor indole alkaloids in these tissues [72, 100].
Interestingly, when compared to the simple model (1), the number of significant markers obtained with the RF approach was much lower for all the metabolites except for δ-tocopherol.
This was a general response in all glycolytic metabolites except for PEP.
Significantly higher concentrations of phthalate metabolites, except for mMP, were found in females as compared to males (Table 1).
Similar(45)
The urinary phthalate metabolites in this population are on average comparable to those measured in pregnant women in other Spanish regions (Casas et al. 2011) and lower compared with those measured in other European pregnancy cohorts with samples collected in 2000 2006, for all metabolites except from MEP, for which lower levels are reported in a French study (Casas et al. 2013b).
All 8 cases that had methamphetamine also had amphetamine present (presumably as a metabolite) except for one case.
We modeled each of the individual phthalate metabolites separately, except for the DEHP metabolites (MEHP, MEOHP, MEHHP, and MECCP), which were combined into their micromolar sum (sum of the individual metabolites concentrations in micrograms per liter divided by the molecular weight of the metabolites) (ΣDEHP).
The correlation between EIA and GC-MS measurement was excellent for both metabolites (r>0.9), except for 2-hydroxyestrone in postmenopausal women (r=0.6).
For all phthalate metabolites except MEHP, > 95% of subjects were at ≥ LOD; for MEHP, 80% of subjects were ≥ LOD.
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