Sentence examples for metabolites are bound from inspiring English sources
In addition, THC and THC-COOH are predominantly detected in blood plasma, where 95-99% of the metabolites are bound to lipoproteins (Huestis [2007]).
Neither levetiracetam nor its primary metabolites are bound to plasma proteins.
Most circulating vitamin D metabolites are bound to DBP to be transported to target organs.
Under the same conditions, [3H]-benzo[a]pyrene metabolites were bound to DNA, and PBB-induced microsomes enhanced this binding more than six-fold.
In another study, anthracene and formed metabolites were bound to several cell-wall components, such as pectin, lignin, hemicellulose, and cellulose [ 23].
In these studies, a greater fraction of the metabolite is bound so the observed (free) rate decreases at higher substrate concentrations.
The crystal structure of SULT1E1 with PAP and the BDE-47 metabolite 3-OH-BDE-47 bound reveals that the metabolite is bound to the same binding site as E2 and TBBPA.
24 Nearly 100% of both aripiprazole and its active metabolite, dehyro-aripiprazole, are bound to plasma protein.
16, 17 In the circulation, these vitamin D metabolites (25[OH]D and 1,25[OH]2D) are bound to vitamin D-binding protein (DBP).
The major vitamin D metabolites (i.e. 25OHD and 1,25(OH)2D) are bound to DBP (> 95%) or another circulatory protein such as albumin, leaving only a small percentage circulating in its free form (for 25OHD (< 1%) [5,9,10].
