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Exact(5)
A positive shadow price means the metabolite is in excess and can be secreted from the cell.
The essentiality of a metabolite measures how important the metabolite is in the whole metabolic systems or some metabolic processes.
We also evaluated how dispersed the data for each metabolite is in clinical cases with respect to those at the baseline.
The higher the variable importance in the projection value the more important the metabolite is in separation of persons without adenomatous polyps from those with adenomatous polyps.
We assess how informative each metabolite is in each model by estimating the density of the sampling distributions for its correlation loading, d(p C), by bootstrapping the regression model, and the density distribution under the null-hypothesis (X and Y j are independent), d(p C|H0), by randomization of Y j.
Similar(55)
Levels of this metabolite are in contrast to tartaric acid, which was 0.31, 0.32, and 0.26.
Both the prodrug and active metabolite are in clinical trials for hematologic malignancies and/or solid tumors.
The detection of metabolites is in many ways dependent on dietary intake.
A full list of these key metabolites is in Additional file 3: Table S1.
The predominant increase of C18 metabolites is in keeping with similar studies in other model systems (16, 26, 27).
In addition, the quantitative pool sizes of intracellular metabolites were in coordination with each other (Fig. 7).
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