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To go further, Richards et al. examined the hypothesis that the initial hippocampal neuronal loss could be related to a preferential decrease in aerobic metabolism when compared to the cortex.
Finally, stable cell lines expressing a chimeric NR had elevated levels of CYP3A4, CYP2B6 and CYP2C9 mRNAs and CYP3A4-mediated metabolism when compared to the wild-type hepatoma cells.
PET imaging documented that the cognitive task significantly increased whole brain metabolism when compared with the control condition both when given with placebo and with MP.
The AMD sample has a preference for CO2 fixation and simple carbohydrate metabolism when compared to either of the Soudan samples.
Fascinatingly, the hippocampus is known to show, by far, the most severe decrement in metabolism when compared with other brain regions in AD [ 78- 80].
In the free-living stages of O. ostertagi, there were significantly (p = 0.01) more transcripts involved in energy metabolism when compared to the parasitic stages.
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We observed a divergence between change of centrality and connectivity for pathways related to amino acid and carbohydrate metabolism when comparing unicellular and multicellular eukarya, and pathways related to the biosynthesis of secondary metabolites when comparing prokarya and eukarya.
Current research begins to define the variation in the functional aspects of human microbiomes revealing an enrichment of several pathways including carbohydrate and amino acid metabolism [23] when compared to the Kyoto Encyclopedia of Genes and Genomes (KEGG) and Clusters of Orthologous Groups (COG) databases [29].
In contrast to the differences between placebo and MP when given with the cognitive task there were no differences in brain metabolism when MP was given with the neutral non-task condition (whole brain metabolism: 35.8±5 µmol/100 g/min) when compared with the neutral non-task condition when given with placebo (36.6±6 µmol/100 g/min).
This finding reflects a specialization in the metabolism of carbohydrates when compared to other groups.
In endotoxemic mice genetically deficient in MIF, glucose metabolism is almost normalized when compared to wild-type mice [ 96].
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metabolism when known
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