Sentence examples for metabolism reduction from inspiring English sources

Many experimental data show that mild hypothermia can exert neuroprotective effects through multiple mechanisms of action: decrease of cerebral metabolism, reduction of apoptosis and mitochondrial dysfunction, slowing of the cerebral excitatory cascade, decrease of local inflammatory response, reduction of free oxygen radicals production, and decrease of vascular and membrane permeability.

Despite its seemingly fundamental and indispensable role in cellular metabolism, reduction of SMN leads to a specific neurodegenerative profile associated with this disease [1], [15], [16], [17], [18].

While differences exist in the patterns of in vitro and in vivo metabolism, reduction of 7KC to 7βOHC appears the predominant reaction in vivo.

Other beta-blocker benefits in heart failure potentially include improved cardiac myocyte metabolism, reduction in apoptosis, reduction in atrial and ventricular arrhythmias, and reduction in myocardial ischemia and/or hibernation.

Before the recent lengthening of life span, individuals in the ancestral environment died well before this metabolism reduction program resulted in clinical AD, thus there was never any selective pressure to keep adaptive changes from progressing to a maladaptive extent.

The lower glycerol production may be explained by the fact that, for yeast metabolism, reduction of furfural to furfuryl alcohol is preferred to glycerol as a redox sink [ 15, 39].

In the 18F-fluorodeoxyglucose positron emission tomography study by Fumal et al. [25], patients with MOH who underwent successful withdrawal from acute medications had greater metabolism reductions in the OFC after withdrawal than they did before withdrawal, leading the authors to conclude that the latter could predispose a subgroup of migraineurs to overuse analgesics.

Following this model, it can be hypothesized that studies that simultaneously assessed these factors will observe increases in oxidative stress accompanied by associated corresponding alterations in FA metabolism (reductions in long-chain PUFAs and increases in SFAs, MUFAs and LPOs) and the 1-C cycle (increased glutathione and homocysteine and decreased folate) (Fig. 4).

Interestingly, it has been documented to be a broad and powerful regulator of ROS metabolism, because reduction in PGC-1α paralleled with a decrease in antioxidant enzymes [ 18].

The combination of effects is essential for the overall action of dietary polyphenols where the consequence is maintenance of normal body metabolism and reduction in the risk of developing type 2 diabetes.

This may be caused by inhibitory effect of metal ions on enzyme activity of ascorbic acid metabolism and reduction of its pool due to the ROS neutralization and its use for plant growth and development, which was confirmed by studies on other plants [7, 35].