Exact(5)
It is well established that HGF can alter the hemodynamics and metabolism of normal and malignant c-MET-expressing tissues [37, 38], and it has been gradually recognized that HGF has high binding affinity and specificity to c-MET.
But, how the metabolism of normal proliferating cells and cancer cells differ has not yet been completely elucidated.
Adjacent cartilage did not show any degeneration in any of the samples examined, indicating that etanercept does not affect metabolism of normal cartilage.
While the effects of autophagy in genetically obese mice and in mice fed high-fat diets seem consistent, a role for autophagy in lipid metabolism of normal mice remains controversial.
Autophagy inhibition did not affect the metabolism of normal cells in a nutrient-sufficient microenvironment (Supplementary Figures 7 and 8), but prominently suppressed the metabolism of tumor cells in a nutrient-deprived microenvironment.
Similar(3)
The trapped F-FDG in cells can reflect glucose metabolism profile of normal tissues and lesions [ 40].
Here we review such topics as suppression of epigenetic silencing of a large number of non-coding RNAs, role of p53 in suppression of the senescence phenotype, inhibition of oncogenic metabolism, protection of normal cells from chemotherapy and even tumor suppression without apoptosis and cell cycle arrest.
The lipid metabolism of a normal rat and a mouse is primarily based on high-density lipoprotein (HDL) rather than on LDL as in humans, which might be attributable to resistance to atherogenesis [ 122].
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