As the most well-understood methylotroph, M. extorquens AM1 is a potential platform for converting methanol to biofuels, building on the elucidation of pathways involved in C1 and C2 metabolism and development of tools for metabolic engineering.
We show that endosymbiont dynamics parallels numerous transcriptional changes in weevil developing adults and affects several biological processes, including metabolism and development.
These results extends the observations of Otegui et al [ 40] and Mitsuhashi et al [ 43] and suggest that metabolic engineering efforts aimed at reducing phytate content in Brassica must consider endosperm metabolism and development.
Changes in the cytoskeleton can lead to changes in cell shape, movement, metabolism, and development.
Phosphate (Pi) is an essential, but limiting macronutrient that plays critical roles in plant metabolism and development.
Clinical effectiveness of gemcitabine in pancreatic cancer is hindered due to its rapid plasma metabolism and development of chemo-resistance.
Transcriptome analysis using Osmyb4 overexpressors showed that expression of genes associated with cellular defense and rescue, metabolism and development were changed in the overexpressors.
Humic substances (HS) are the major components of soil organic matter (SOM) and positively affect crop production [1] by playing pivotal roles on both soil-plant system [2] and plant metabolism and development [3-6].
Whether the upregulation of hsp70 in early embryogenesis would protect the embryonic cells or ensure proper folding of proteins that are required for normal metabolism and development needs further studies.
In Aspergillus oryzae RIB40, HstD (a homolog of Sirtuin) coordinates secondary metabolism and development through control of the global regulator LaeA, suggesting that member of signaling pathway connects acetylation modification with its modulation processes (Kawauchi et al. 2013).
However, recent studies have shown increasing evidence of functional plasticity among Alba family of proteins that widely range from genome packaging and organization, transcriptional and translational regulation, RNA metabolism, and development and differentiation processes.
