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As described in the previous sections, cancer cells exhibit critical metabolic transformations induced by mutations that result in cell cycle deregulation associated with enhanced cellular stress.
Cancer cells exhibit critical metabolic transformations induced by mutations leading to gain-of-function of oncogenes and loss-of-function of tumor suppressor genes that result in cell deregulation associated with increased cellular stress.
Cancer cells exhibit an array of metabolic transformations induced by mutations leading to gain-of-function of oncogenes and loss-of-function of tumor suppressor genes that include increased glucose consumption, reduced mitochondrial respiration, increased reactive oxygen species generation and cell death resistance, all of which ensure cancer progression.
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Active general covariance considers the dual point transformations induced by coordinate transformations.
This also indicated that γ → ε transformation was important for transformation induced plasticity effect.
The hyperspiny transformation induced by either lesion or block of activity is reversible.
Indeed, transformation induced a significant increase in RhoA phosphorylation in 2BN11 cells.
These generic metabolites represent whole classes of structurally similar metabolites that undergo the same metabolic transformations in vivo.
Reactor cycle studies demonstrate that the three sludges carried out metabolic transformations typical of EBPR (Table 1, Fig. S1).
Metabolic transformations of selected pesticides illustrating various types of reactions in plants and animals are discussed.
The selection process taking place after transformation induces these additional differences in the plant material.
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