Sentence examples for metabolic transformations are from inspiring English sources
Hence, it is of interest to define which metabolic transformations are catalyzed by these bacteria, as they might be particularly relevant for understanding the global impact of the gastrointestinal microbiota on human health.
The metabolic transformation is a switch from an oxidative metabolism to a glycolytic metabolism that is reversibly dependent on external glucose concentrations [ 2].
The involvement of P450scc in adrenal metabolic transformation was confirmed by the inhibition of this process by DL-aminoglutethimide.
The disadvantage of fingerprint-based data mining method is that generic metabolic transformation rules are so simple that they cannot describe complex reaction types and cannot cover larger chemical reaction space.
Furthermore, the strength and durability of the C-F bond compared with the С-Н bond (116 and 100 kcal/mol respectively) allows undesirable metabolic transformations to be avoided.
The transformations are startling.
In this review we summarize our current understanding of how 'metabolic transformation' is linked to oncogenic transformation, and why inhibition of metabolism may prove a cancer′s 'Achilles' heel'.
Use of a prodrug that is not pharmacologically active until it undergoes a metabolic transformation has been shown to decrease oropharyngeal effects and might result in improved pulmonary targeting (Hübner et al. 2005).
However, in the present study, we show that oncogene-induced insulin-independence also represents a metabolic transformation, which is a result of oncogene-regulated changes to gene transcription.
Understanding the metabolic changes associated with somatic cell reprogramming might shed light on the "metabolic transformation" that is required to support not only the increased biosynthetic needs of the tumor cell but also to enable the acquisition of stemness properties in cancer stem cells (CSCs).
Characterizing the biological effects of metabolic transformations (or biotransformation) is one of the key steps in developing safe and effective pharmaceuticals.
