Sentence examples for metabolic shift of from inspiring English sources

These peculiarities are commonly attributed to the defective vascularization of solid tumors that leads to an hypoxic environment that contributes to a metabolic shift of cancer cells metabolism towards glycolysis, with the consequent release of lactic acid in the extracellular milieu [ 11].

We have shown before that Survivin-mediated resistance against chemotherapeutic agents is caused by the shutdown of mitochondrial complex I activity and a metabolic shift of neuroblastoma cells from oxidative phosphorylation to aerobic glycolysis.

In addition to the PrfA*-related metabolic shift of L. monocytogenes towards glycerol utilization, our data indicate that the competitive defects exhibited by prfA* mutants in broth culture were exacerbated under conditions of osmotic and/or acid stress (Fig. 3).

Thus, an increase in its production within gastric mucosa may be a compensatory response to metabolic shift of obesity.

The Dos regulon comprises ~47 genes thought to have crucial roles in the metabolic shift of Mtb to the persistent state (Refs 60, 147).

CDDP-induced cytostatic effects were associated with a metabolic shift of cancer cells towards accumulation of MRS-detected neutral lipids, whereas the total choline profile failed to be perturbed in both cultured cells and xenografts.

Increasing species richness or legume proportions led to significant metabolic shifts of their primary and secondary metabolism summarized in metabolic signatures (Fig. 4).

Indeed, cancer cells display a metabolic adaptation called aerobic glycolysis or "Warburg effect", which consists of a metabolic shift to increase the glycolytic pathway as a main source of ATP, instead of oxidative phosphorylation (OXPHOS), independent of the presence of oxygen [ 12, 13].

It appears that the reduced ROS levels are a result of metabolic shift to beta-oxidation and not due to active ROS detoxification.

In the first of these ('Forward' 1, Figure 2(a)), acidogenesis at pH 5.7 was maintained for 137 hours, after which the pH control was stopped, allowing the natural metabolic shift to the production of the solvents to begin.

To initiate the metabolic shift, control of the pH of the culture via KOH is turned off.