Sentence examples for metabolic rigidity from inspiring English sources

This metabolic rigidity can be overcome by overexpressing PEP carboxylase (PEPC) and/or PEP carboxykinase (PEPCK) or by inactivating genes of the PTS, but the consequent reduction in glucose absorption results in a slower growth rate and, therefore, less overall succinate productivity or production.

The syndromes of malignant hyperthermia and neuroleptic malignant syndrome are characterized by fever, generalized muscular contraction and rigidity, metabolic acidosis and rhabdomyolysis [ 34].

Affected animals can experience upon slaughter a range of symptoms, including skeletal muscle rigidity, metabolic acidosis, tachycardia and fever, similar to the human syndrome.

Upon slaughter, pigs carrying the halothane sensitivity (n) allele at the ryr1 locus can exhibit rapid-onset, severe malignant hyperthermia (MH), experiencing a range of symptoms, including skeletal muscle rigidity, metabolic acidosis, tachycardia and fever, which are due to an enhanced calcium release from intracellular stores.

We postulate that when this happens, the entity (process or object) has features possibly a particular metabolic flux, possibly rigidity, possibly specific conformation features such as a specific proline isomer, absence of isoaspartates in proteins, etc. that can be identified by the degradative machinery.

To draw conclusions about the likelihood of MH among the suspected incidents, the "Clinical Grading Scale" (CGS) established by Larach and colleagues assessed clinical and metabolic parameters, e.g. muscle rigidity, rhabdomyolysis, acidosis, increases in body temperature and cardiac arrhythmias [ 9].

The results of this study support thehypothesis that axial rigidity of bones with metabolic pathologies can be accurately and quantitatively assessed in a rat model by conducting structural rigidity analysis on serial axial images of the affected bone.

One major caveat of the metabolic channeling hypothesis is the inherent rigidity of a multi-enzymatic complex, making any mutation dissociating parts of the tight complex potentially prone to reduce or eliminate its enzymatic activity.

Malignant hyperthermia is a metabolic muscle disease characterized by high fever and extreme rigidity of muscles, usually caused by certain anesthetics or muscle-relaxant medications given during surgery.

In the 81st week, the patient became comatosed (Glasogow Coma Scale 5) with hypertonia, a positive Babinski sign, and neck rigidity, indicative of central nervous system infection or metabolic encephalopathy.

The additional rigidity of a bicyclic structure should also improve its metabolic stability as well as the target binding affinity and specificity.