Sentence examples for metabolic reprogramming plays from inspiring English sources

Here we investigated whether metabolic reprogramming plays a critical role during Hcy-induced T-cell activation.

In addition, metabolic reprogramming of endothelial cells plays an important role in the process of angiogenesis (Goveia et al, 2014).

In the placenta metabolic reprogramming is likely to play a unique and important role in the regulation of fetal growth.

Therefore, dynamic FBA provides a framework for analyzing the transience of metabolism due to metabolic reprogramming and for obtaining insights for the design of metabolic networks.

Oncogene activation plays a role in metabolic reprogramming of cancer cells.

Hypoxia inducible factor-1 (HIF-1) is a key transcription factor that plays major roles in this metabolic reprogramming.

Regardless of the exact role that JA plays in the process, the metabolic reprogramming may be sufficient to explain the lower fitness observed in plants lacking PsbS, since JA-induced responses are known to reduce seed production [ 26].

Two key transcription factors that play major roles in this metabolic reprogramming are hypoxia inducible factor-1 (HIF1) and MYC.

Other important proteins play key roles in the metabolic reprogramming of cancer cells, including the glucose transporter 1 (GLUT1) and the pH regulator carbonic anhydrase IX (CAIX) [ 12].

Importantly, the high frequency of MCT4, when compared with MCT1, indicates that this MCT isoform should play an important role in the metabolic reprogramming of cancer cells towards a hyperglycolytic and acid-resistant phenotype.

This metabolic reprogramming persisted throughout the study period (5 days).