Sentence examples for metabolic redirection from inspiring English sources

Additionally, since pyruvate is mainly assimilated through pyruvate formate lyase (pfl) and forms formic acid and acetyl coenzyme A, metabolic redirection was attempted through gene knockout by Red-mediated recombination to decrease the byproducts of pyruvate metabolism.

This metabolic redirection to aerobic glycolysis and lactate production offers several benefits for the proliferating cell [10].

Outside of the process of cell division, this same metabolic redirection occurs during episodes of hypoxic stress.

Complicated hormone crosstalk modulates the fine-tuning of transcriptional reprogramming and metabolic redirection, resulting in production of antimicrobial metabolites, enzyme inhibitors and cell wall refortification to restrict further pathogenesis.

Metabolic flux redirection from competing pathways also stimulated folic acid production.

When this designed bypass was expressed at the appropriate expression level associated with the conditional metabolic flux redirection, pyruvate accumulation was prevented, and the isopropanol production titer and yield were improved.

This finding highlights the general potential of metabolic flux redirection towards the pentose phosphate pathway, which could be used for metabolic engineering of the biotechnological synthesis of (1) aromatic amino acids and (2) chemicals whose synthesis depends on intracellular NADPH supply.

In the current study, we focus on the role of the intracellular pyruvate pool in the redirection of metabolic fluxes at this important node.

At the end of the chronological 'hunting' age, there was a gradual redirection of metabolic processes toward energy conservation in anticipation of aging.

Unexpectedly, PHS1×NDPS1 fruits showed recovery of lycopene levels compared to NDPS1 fruits, suggesting that redirection of metabolic flux is only partially responsible for the reduction in carotenoids.

Thus, Sir2 overexpression does not promote survival of cells lacking GAPDH by redirection the metabolic flux through the PPP.