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Heterologous expression of these cryptic gene clusters combined with comparative metabolic profiling provides an important means to identify potentially novel compounds.
Our metabolic profiling provides a snapshot of the complex human metabolome.
Metabolic profiling provides semi-quantitative data, typically as chromatographic peak areas, rather than absolute quantitation where metabolite concentrations would be reported.
Our work shows that mining the genomes of Lysobacter species in combination with metabolic profiling provides novel insights into the genomic and metabolic potential of this widely distributed but understudied and versatile bacterial genus.
In conclusion, mining the genomes of Lysobacter species in combination with metabolic profiling provides novel insights into the genomic and metabolic potential of this widely distributed, versatile but understudied bacterial genus.
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Genomic – based technologies such as metabolic profiling provide a new means to explore the combination of multiple metabolites as a biomarker, which may allow for more precise outcome predictions.
An increased understanding of cancer metabolic profiles provides hope that a novel class of therapeutic agents may be developed for cancer therapy.
Compared to conventional markers, such as AST, ALT, and CK, the urine metabolic profile provided clearer distinction between the pre- and post-treatment groups treated with toxic levels of simvastatin.
In turn, this has led to the concept of 'global metabolic profiling', which provides a unique overview of the metabolic state of an individual.
However, provided that these results can be reproduced, metabolic profiling may provide a starting point for mechanistic investigations into the pathogenesis of RA.
The disparity between the diversity patterns represented by AFLPs and by metabolic profiles thus provides insights into the processes that led to the composition of the current sesame genome.
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