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Consequently, we designed this study to evaluate the linkage between the distribution of bGDGTs, their biological sources and inferred metabolic processes based on the distribution and abundance of bGDGTs, pertinent water chemistry, the nirS gene (possibly in Beta- and Gamma-proteobacteria) and available 16S rRNA (tag) gene pyrosequencing data from 37 Tibetan hot springs.
Each of the GS genes appears to participate in different metabolic processes, based on where and how they are expressed.
Up to now, several published papers have studied the function modules or metabolic processes based on experimental generated PPI sets.
In module 1, s1_contig13083 co-expresses with SPY-like and CUL4-like and involved in macromolecule metabolic and cellular metabolic processes based on GO annotation.
A total of 1,337 genes of the C. crescentus genome are classified under primary and cellular metabolic processes based on UniProt-GOA [ 30].
The potential function of the majority of the annotated DEGs was assigned to metabolic processes based on sequence similarity of genes in public databases.
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Seventy-one of these pairs were annotated with a majority of the sequences that were associated with macromolecule metabolic processes and regulation of biological processes based on the sequence distribution of Gene Ontologies (Table 1).
However, one individual GO term, "alcohol metabolic process" which was based on four genes (ALDH2, PRDX1, PDIA and PNPO), was significant (FDR = 0.06).
This principle was given analytical support by formulating a mathematical model of the aging process based on a formal representation of the metabolic stability concept (Demetrius 2004).
The model, which incorporates key transport and metabolic processes and subcellular compartmentalization, is based on dynamic mass balances of 30 chemical species in both capillary blood and tissue cells (cytosol and mitochondria) domains.
Lee et al constructed a disease network based on metabolic processes, whereby two diseases are linked if their mutated enzymes catalyze adjacent metabolic reactions.
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