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However, as the stress level increases or stress becomes constant, more adjustments are necessary to achieve the same goal, which means that activity of more genes (or whole metabolic pathways) needs to be adjusted.
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A complete genome of the bacterium Baumannia cicadellinicola and a partial sequence of Sulcia muelleri reveal that Baumannia has the metabolic pathways needed to provide its insect host with vitamins, but has lost those for the essential amino acids.
These responses in metabolic pathways need to be examined in future experiments.
This great extent of host dependency may be pressuring symbionts to retain the necessary metabolic pathways needed by the host.
Differences in the use of various metabolic pathways need to occur in different developmental or growth response events, but these are differences in degree.
In order to understand the highly redundant phospholipid synthethic pathways and eventual mechanism of resistance to various drugs, an organism specific kinetic model of these metabolic pathways need to be developed in Plasmodium species.
Such fundamental dependency on the most upstream external compounds should intrinsically constrain sustained evolutionary elongation of multi-step metabolic pathways needed for color elaboration unless the metabolic network gains robustness – the ability to synthesize the same carotenoid from an additional dietary starting point.
This indicates that, to maintain an optimal or high growth rate, all efficient metabolic pathways need to be exploited to convert metabolic resources into the biomass components, leaving no freedom for the metabolism to adjust the priority of producing flavins versus cytochrome c.
Improve the efficiency of C3 metabolic pathway needs to know the functions of proteins involved in C3 pathway.
Light and temperature inputs entrain the circadian clock, allowing plants to coordinate metabolic pathways that need to be attuned to the day.
To predict metabolic pathways, we need to represent metabolic data as a network (or a graph, to use the mathematical term).
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