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Fig. 5 Changes in metabolic pathways induced by Fe deficiency in rice roots.
A transcriptomic analysis compared gene expression to identify the metabolic pathways induced by this environment, versus control cultures maintained in spent culture medium.
This finding is supported by the results of an earlier study in mouse which showed that chemical inhibition of some metabolic pathways induced oocyte maturation [ 40].
Taken together, it suggests that the significant correlation between the low values of DOC and the drastic decrease of actinobacterial strains may be attributed to the loss of related metabolic pathways induced by heavy metal contamination.
In this regard, the recent emergence of metabolomics technologies offers a means to systematically measure thousands of low-molecular-weight compounds in order to provide a global view of alterations in metabolic pathways induced by a given perturbation, whether resulting from a gene mutation or disease onset.
The metabolic pathways induced under drought in A. thaliana have been associated with abscisic acid (ABA -dependent ABA -dependentndent pandways governing drought-inducible gene expression [ 41, 42] as well as the existence of an interconnection between both signaling pathways [ 43, 44].
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We aimed at determining, whether the altered metabolic pathways induce the growth arrest by energy shortage, or whether other mitochondrial functions, like generation of Fe-S cluster proteins, are more relevant for the pica phenotype.
According to our results suggest that the ethylene signaling involved in the secondary metabolic pathway induced the accumulation of phenolic compounds and catechin galloylation and reduced antioxidant enzyme activity in the tea seedlings.
Exercise induced changes in muscle metabolic pathways have previously been shown to markedly improve glucose uptake and mitochondrial function, in all age groups [ 13].
Further evaluation of the metabolic and transport pathways induced in B. anthracis during iron starvation, and other host specific cues, may provide insight into the specific metabolic changes the bacterium requires for adaptation to life within a mammalian host.
By contrast, anaerobic metabolic pathways have received less attention.
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