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Furthermore, some metabolic pathways appear to be missing altogether from diatoms [9].
The analysis of metagenomic sequence data for community structure and the taxonomic distribution of identified genes is an important first step, analogous to answering the question "who's there?" A seminal, early metagenomic work demonstrated that certain genes and metabolic pathways appear to be depth specific.
The genes for several vital metabolic pathways appear to be missing in Nanoarchaeum [ 1].
These two metabolic pathways appear to be regulated by iron in opposing manners.
In general, breast tumour metabolic pathways appear to be different compared with the normal cells from which they arise.
In some cases, only single enzymes are recruited, whereas in other instances, entire metabolic pathways appear to have been co-opted for new function.
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The most prominent alterations in KEGG defined metabolic pathways appeared to be in (i) alanine, aspartate and glutamate metabolism (3 metabolites [ko00250]), (ii) phenylalanine, tyrosine and tryptophan metabolism (3 metabolites [ko00360]), (iii) purine metabolism (2 metabolites [ko00230]) and (iv) butanoate metabolism (2 metabolites [ko00650]).
The issue of analyzing biological processes spanning several metabolic pathways appears in many contexts.
However, the regulation of metabolic pathways appeared to be less prominent than that of the inflammatory pathway in our studies.
A number of other metabolic pathways appeared to be altered by TNBS colitis, including purine de novo biosynthesis, arginine and heme catabolism.
Thus, an intact purine metabolic pathway appears to be very important for the growth intracellularly and in vivo of F. tularensis.
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