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One informative approach that has not yet been used to study the metabolic adaptations following RYGB is metabolite profiling, despite the fact that this approach has successfully generated new knowledge regarding the metabolic modifications associated with obesity and diet-induced weight loss [13] [16].
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5– 10 Other related modifications associated with menopause, such as increased blood pressure, reductions in glucose tolerance, atherogenic changes in the lipid and coagulation profiles, and impairment of endothelial function, are common and can also increase the incidence of metabolic syndrome.
DNA methylation and histone modifications are important epigenetic modifications associated with gene (dys)regulation.
Thus, adaptation to certain environments may involve numerous metabolic modifications that may lead to detectable associations although the gene products and the associated metabolite reside in unlinked metabolic pathways and thus are only connected through higher level functional integration.
Introduction In stress situation, inflammation causes several metabolic modifications.
The effect of these metabolic modifications on citrate production varied.
Indeed, several studies have shown that metabolic modifications occur during severe injuries and could lead to a metabolic hibernation.
However, we also do find an effect of these metabolic modifications on itaconic acid production.
Such information is of high significance for the metabolic engineers, as it may help them in designing further metabolic modifications.
The term lipodystrophy was initially used to summarize these clinical and metabolic modifications [ 2].
Metabolic modifications, such as weight loss and maintenance, increased physical activity, and β-cell rest.
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