Sentence examples for metabolic models was from inspiring English sources
In combination with landmark physiological insights and increased output of omics-data, a good basis for the creation of refined genome-scale metabolic models was created.
Cell-specific lipid production of each of the metabolic models was validated.
A first metabolite-centric approach for the analysis of genome-scale metabolic models was introduced in 2007 [ 32] and expanded in 2009 [ 33].
The first release of cell type-specific metabolic models was automatically constructed from a generic GEM and resulted in GEMs for 69 normal and 16 cancer cell types (2).
For all simulations, the biomass function of each of the metabolic models was set to a physiologically relevant lower bound determined from the cells' in vitro growth rate [ 17- 19].
The meeting "Challenges in experimental data integration within genome-scale metabolic models" was held at the Institut Henri Poincaré, Université Pierre et Marie Curie, Paris, October 10th and 11th, 2009 [ 1].
Molecular level metabolic models were constructed to represent the central metabolism of three functional guilds thought to be important to material and energy flows through this community [ 12].
Genome-scale metabolic models are increasingly becoming available for a variety of microorganisms.
As larger metabolic models are developed with increasing genetic information and experimental validation, the demand to incorporate kinetic information increases.
For model organisms metabolic models are well established, with many manually curated genome-scale model reconstructions, gene knockout studies and stable-isotope tracing studies.
Microbial transcriptomics may yield improved predictions of metabolic processes and enzymatic pathways present in well-defined environmental conditions, but interpretations of such metabolic models are cumbersome [23], [24].
