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It adds that "there appear to be other metabolic mechanisms that compensate for the poor metabolism of these drugs by CYP2D6".
Differences in substrate and purine metabolism following single exercise protocols may elucidate possible metabolic mechanisms that will help explain the negative energy balance and fat loss in HIIE training.
In this context, we aimed to determine the metabolic mechanisms that contribute to ivermectin resistance in a resistant strain of this species.
Through metabolic mechanisms that are not fully understood, women experience greater physical damage from the same amount of alcohol than do men.
The design of inserts that can be used in the measure of bioenergetics in small numbers of cells in an organotypic state may be useful for evaluation of new drugs and metabolic mechanisms that underlie airway diseases.
However, algae are not exoelectrogens and the conventional mediators do not perform well in the extraction of the redox potential for algae-based MFCs because the redox species are produced through the metabolic mechanisms that take place in membrane-surrounded cell organelles in algae such as mitochondria and chloroplasts [74].
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As a response to draining electrons away from NADH, a metabolic mechanism that regenerates NADH from NAD+ at a high rate had to be activated to restore the redox balance for survival (growth).
Selection began to operate not simply on genes for ascorbic acid synthesis but also across a distributed network of sensory biases, behavioural inclinations and digestive-metabolic mechanisms that increased the probability of obtaining ascorbic acid from the environment.
Researchers said that it appears the vaccine affected a metabolic mechanism that increases consumption of glucose by cells.
We chose to minimize the variance of the error variables (and not their total sum) to account for potential metabolic regulation mechanisms that are not explicitly incorporated in the model (e.g. allosteric regulation) and may systematically affect the metabolic flux.
In addition, the anuria precluded metabolic compensatory mechanisms that require functioning kidneys.
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