Sentence examples for metabolic intermediaries from inspiring English sources

Disruption of urea synthesis by inborn errors of metabolism leads to hyperammonemia and accumulation of other metabolic intermediaries (Summar et al 2005).

When the enzymatic sets exhibit a rhythmic behavior, all the metabolic intermediaries oscillate with the same frequency but different amplitudes [33].

Indeed, microbiota regulates the guts' barrier function and motion, influences nutrient absorption, produces important metabolic intermediaries, including vitamins, and modulates local and systemic inflammation through innate immunity.

The increase in glucose uptake by TNBC cells (Additional file 2: Figure S1B) will help to provide metabolic intermediaries essential for lipid and nucleic acid syntheses (NADPH and PPP pathway) required for their active proliferation.

Therefore, fructose may indirectly influence appetite and reward through changes in the levels of peripheral neural input or metabolic intermediaries modifying the activation of brain regions implicated in appetite and reward.

Whether this cortical response to fructose is due to effects mediated by GLUT2 and GLUT5 carriers in the BBB or in local glial cells, due to increased osmolality, or is the indirect result of changes in the levels of peripheral neural input or metabolic intermediaries is yet to be understood.

The purine ribonucleoside adenosine (Ado) is a naturally occurring metabolite that is ubiquitously distributed throughout the body as a metabolic intermediary.

In this putative pathway, the first metabolic intermediary (GDP-L-gulose) is generated from GDP-D-mannose by action of GDP-mannose-3′,5′-epimerase (E.C. 5.1.3.18), subsequently GDP-L-gulose is transformed to L-gulono-1,4-lactone throughput four sequential biochemical reactions.

Canonical pathway analysis of the fetal liver signature demonstrated increases in functions important in cell replication and DNA fidelity whereas most metabolic pathways of intermediary metabolism were under expressed.

In summary, broad metabolite profiling of non-diabetic vs. type 2 diabetic plasma, in conjunction with our previous acylcarnitine profiling, indicates that T2DM is a disease that disrupts multiple intermediary metabolic pathways including amino acid metabolism.

Augmentation of creatinine and sustenance of elevated plasma urea concentrations in llamas when fed the LP diet must reflect distinct metabolic adaptations of intermediary protein and/or nitrogen metabolism, not observed in the true ruminants.