Will survival be better for patients treated more intensively because they have a poor interim metabolic response?
However, such treatment modification using the interim metabolic response remains controversial, and its clinical use is not permitted, except in clinical trials.
One potential early prognostic marker that this study investigated is metabolic response based on interim and posttreatment FDG-PET.
Also for aggressive non-Hodgkin lymphoma, the metabolic response determined on interim PET is a stronger prognostic factor than the IPI.
Overall, 3069 participants (27.3%) from the Australian Diabetes, Obesity and Lifestyle study were classified as having metabolic syndrome according to the joint interim statement for metabolic syndrome published in 2009, and free of diagnosed cardiovascular disease or frank diabetes.
14 Only participants free of cardiovascular disease or diabetes, or both, at baseline, and classified as having metabolic syndrome according to the joint interim guidelines 15 (published in 2009) were included in the model.
The diagnosis of the metabolic syndrome was based on the joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention National Heart , Lung, and Blood Institute American Heart Association World Heart Federation International Atherosclerosis Society and International Association for the Study of Obesitysity [ 31].
In 2009, an additional definition of metabolic syndrome was proposed as a joint interim statement (JIS) by several organizations in an attempt to harmonize the definition of metabolic syndrome (5).
Metabolic syndrome was defined by the joint of interim statement of the International Diabetes Federation and the American Heart Association/National Heart ,Lung, and Blood Institute.
To test for metabolic syndrome, we used the criteria from the joint interim statement by Alberti et al. (23).
For metabolic syndrome diagnosis, we used the criteria of the recently published joint interim statement (2009).
