Sentence examples for metabolic interconnection from inspiring English sources

Its regulation target, the pyruvate dehydrogenase (PDH) multienzyme complex, plays a key role in the metabolic interconnection between glycolysis and the citric acid cycle [ 31].

Although the effects of AdoHcy on phospholipid composition have not been addressed, its accumulation causes an increase in TAG synthesis and LD content (Malanovic et al. 2008), further underscoring the metabolic interconnection between phospholipid and TAG homeostasis discussed above.

The main results presented in this paper are recapitulated in Figure 10, in which the metabolic interconnections of glutamine (Figure 10A) and the effects that glutamine deprivation has on signaling pathways and molecular events of the G1 to S transition, both in normal/reverted or in K-ras transformed cells, are described (Figure 10B and C).

Moreover, because of the tight metabolic interconnections among different members of the sphingolipid family, it is important to perform such measurements simultaneously on multiple rather than individual components of the family.

This review aims at providing novel insight into the regulatory pathways of autophagy in response to glucose and amino acid deprivation, as well as their tight interconnection with metabolic networks and redox homeostasis.

Small variations in phenotype arise in part because the interconnections of metabolic pathways in the organism are so complex that variation in proteins that are not directly part of the melanin production pathway may nevertheless have an effect on the rate of melanin formation.

In the future, the interconnections between metabolic changes and the better known protein posttranslational changes need to be explored.

This study and its findings may be useful and provide some basic information regarding our understanding of complex pathological interconnections between metabolic heritage and modern environment.

Useful hints to disclose the origin and evolution of ancestral metabolic routes and their interconnections can be obtained by comparing sequences of enzymes involved in the same or different metabolic routes.

This is in line with the concept that the immune and metabolic systems are tightly interconnected and that this interconnection is pivotal in the development of co-morbidities of obesity.

Indeed, it is quite possible that the biochemical flexibility of the ancestral enzymes might result in an extreme interconnection among different metabolic routes.