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The one "metabolic fault" shared by all of the volunteers was a high CRP.
It is seen in anemia responsive to vitamin B6 (pyridoxine), where the anemia probably results from a metabolic fault in the synthesis of the heme portion of hemoglobin.
Alternatively, the metabolic fault may be associated with aging and the concomitant deterioration of control mechanisms, as in the loss of calcium from bone in the condition known as osteoporosis.
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That these late-developing metabolic diseases also have a genetic basis that is, that there is an inherited tendency for the development of the metabolic faults involved seems to be definitely the case in some instances but remains either incompletely understood or uncertain in others.
Metabolic deficiencies.
"Goodbye, metabolic.
Go! Go! Go! Goodbye, metabolic.
"My fault.
Double fault.
Fault free".
His fault.
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