Sentence examples for metabolic failures from inspiring English sources
In particular, OA-triggered short human GLP-1 (shGLP-1) expression in hepatogenous diabetic mice rapidly and simultaneously attenuated many disease-specific metabolic failures, whereas OA or shGLP-1 monotherapy failed to achieve corresponding therapeutic effects.
New-onset renal, respiratory, central nervous system, coagulation and metabolic failures were also individually associated with pressor delays >14 hours.
Despite that the overall risk of organ failure was not affected by diabetes, and the risks of renal and metabolic failures were increased.
A poorer metabolic reserve and a higher prevalence of chronic renal disease in diabetes may explain the higher risk of renal and metabolic failures in diabetic AP patients.
In vitro studies suggest that glutamine might also cause metabolic failure within mitochondria, having been transported into mitochondria where it is metabolized to glutamate and ammonia [ 23].
The main reasons of admission were: hematologic failure (in particular hemorrhagic) (29.9%), metabolic failure (19.5%), renal failure (11.0%), neurological failure (11.0%) and sepsis (10.4%).
Therefore, it is postulated that the predominant physiologic cause of intravascular sickling or rheological impairment in those with heterozygous sickle genes (HgbAS) is the low level of oxygenation in the cell and a decreasing pH (acidosis) which in a positive feedback loop then trigger skeletal muscle metabolic failure or rhabdomyolysis [3].
Metabolic failure: Low pH with high lactate (eg, pH <7.30 and plasma lactate > upper limits of normal).
Not surprisingly, metabolic failure at the cellular level is associated with worse clinical outcomes.
These complications included respiratory failure, renal failure, gastrointestinal bleeding, metabolic failure (details unknown), sepsis, or hypoxia [ 43, 46].
Increased cerebral L/P unmasking metabolic failure has been shown to preceed rises in ICP, underscoring its importance within bedside metabolic monitoring [ 16].
