Your English writing platform
Discover LudwigSuggestions(5)
Exact(6)
The concept of de novo metabolic engineering through novel synthetic pathways offers new directions for multi-step enzymatic synthesis of complex molecules.
Systems biology provides new approaches for metabolic engineering through the development of models and methods for simulation and optimization of microbial metabolism.
To generate a DGLA-producing strain, fatty acid reconstitution in Aspergillus oryzae was performed by metabolic engineering through co-expression of codon-optimized Pythium Δ6-desaturase and Δ6-elongase, which had high conversion rates of substrates to respective products as compared to the native enzymes.
Metabolic engineering through systems biology has been complimented, and its application expanded in both scope and success.
Finally, RehMBEL1391 was successfully used to identify gene knockout targets for metabolic engineering through in silico gene knockout simulation for the production of 2-methylcitric acid.
Using S. cerevisiae Ethanol Red as platform, the by now classical approach commenced with rational metabolic engineering through transformation with a cassette containing the XI gene from Clostridium phytofermentans, followed by random mutagenesis using EMS with hydrolysate and xylose as selective criteria.
Similar(54)
Through metabolic engineering microorganisms can be engineered to produce new products and further produce these with higher yield and productivities.
Metabolic engineering of microorganisms through the expression of one or more plant genes, often in connection with genetic alteration of the whole cell metabolism, has become an increasingly important route for small molecule synthesis.
Through metabolic engineering of E. coli metabolism, succinate production was greatly elevated by (1) blocking pathways for the synthesis of competing by-products lactate, ethanol, and acetate and (2) expressing Lactococcus lactis pyruvate carboxylase to drive the generation of succinate from the pyruvate node (as opposed to that of phosphoenolpyruvate).
Previously, we constructed a xylose fermenting strain of Saccharomyces cerevisiae through metabolic engineering and enhanced its xylose utilization capability through evolutionary engineering.
However, to harness this potential through metabolic engineering, a deeper understanding of photosynthetic metabolism is required.
More suggestions(15)
metabolic acidosis through
metabolic resistance through
metabolic dysfunction through
metabolic pathway through
metabolic control through
metabolic energy through
metabolic obesity through
metabolic flux through
metabolic disease through
metabolic disruption through
metabolic homeostasis through
metabolic syndrome through
metabolic regulation through
metabolic network through
metabolic flow through
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com