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To this end, metabolic engineering provides the technological platform for enhancing NP production in these engineered heterologous hosts.
Metabolic engineering provides a convenient framework for such integration.
Metabolic engineering provides a means for fermentation improvements.
Recently, metabolic engineering provides effective strategies to develop PPD producers.
Metabolic engineering provides an effective alternative to the random mutation for strain development.
Because of the existence of acrylic acid pathways in some microorganisms, strain improvement and metabolic engineering provides also a possibility to produce acrylic acid directly from biomass by fermentation.
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Also, the theoretical formalisms of metabolic engineering provided a basis for optimally routing its biochemical flux.
However, recent successes in construction of high-yielding medium chain fatty acid producing E. coli strains, rooted in different features of systems metabolic engineering, provide an emerging case study of design methods for effective strain design (Dellomonaco et al., 2011; San and Li, 2013; San et al., 2011; Zhang et al., 2012b).
This study suggests possible avenues for metabolic engineering and provides comprehensive, integrated systems biology datasets that will be useful for future metabolic modeling and strain development endeavors.
Advances in molecular biology and metabolic engineering have provided new insights and techniques for increasing biomass and biohydrogen production, and recent efforts in synthetic biology have demonstrated that complex regulatory and metabolic networks can be designed and engineered in microorganisms.
A broad view of currently used and potential new sources for betalains, including utilization of natural sources or metabolic engineering, is provided together with a summary of potential applications of betalains in research and commercial use.
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