Sentence examples for metabolic engineering including from inspiring English sources

Here, we highlight the crucial factors for subcellular-localization-based strategies in plant metabolic engineering including substrate availability, enzyme targeting, the role of transporters, and multigene transfer approaches.

Approaches such as the exploration for more diverse isolates having fast growth rates, metabolic engineering including gene cloning, and growing thraustochytrids on alternate low cost carbon source, will further enhance the biotechnological potential of thraustochytrids.

Further metabolic engineering, including preventing Rh2 degradation and increasing UDP-glucose precursor supply, increased Rh2 production to 2.90 mg/g DCW, which was more than 900-fold higher than the starting strain.

In his Science paper, Keasling discusses the formidable roadblocks that stand in the way of a future in which microorganisms and molecules can be tailor-made through metabolic engineering, including the need for "debugging routines" that can find and fix errors in engineered cells.

There have been numerous successes of metabolic engineering, including the well publicized biosynthesis of artemisinic acid, a precursor to the antimalarial drug artemisinin [1], and thebaine, a precursor to hydrocodone and morphine [2].

In this review, we propose simultaneous transport and metabolic engineering, including new global cellular metabolic engineering techniques, as a powerful approach for the development of an economical hexose and pentose cofermenting yeast.

Rational metabolic engineering includes three primary strategies to divert carbon and electron flow from byproducts to increase ethanol yield and purity: introduce heterologous genes, increase the expression of native genes, and disrupt genes required for competing pathways in mixed fermentations [ 10].

These findings have implications for downstream applications of metabolic oligosaccharide engineering, including imaging and proteomics.

In this work, metabolic engineering methodologies including medium component analysis, 13C-labeling experiments, and computer-aided simulation analysis were applied to characterize the metabolic phenotype of soft tissue sarcoma cells derived from p53-null mice.

Then, two metabolic engineering approaches, including deletion of the repressor gene papR3 and chromosomal integration of an extra copy of the PI biosynthetic gene cluster (BGC), were employed to improve PI production.

In this review, systems metabolic engineering strategies including pathway-focused approaches, systems biology-based approaches, evolutionary approaches and their applications in two major amino acid producing microorganisms: Corynebacterium glutamicum and Escherichia coli, are summarized.