Metabolic efficiency is crucial for β-cell function as glucose metabolism is tightly coupled to the control of insulin secretion [ 11].
The regulatory mechanism coordinating the metabolism of carbon and energy sources in order to maximize the metabolic efficiency is called carbon catabolite control, i.e., carbon catabolite repression (CCR) and carbon catabolite activation (CCA).
Metabolic efficiency is usually unknown and typical measures of intake and activity are susceptible to both bias and error.
The actual advantages – or lack of them – conferred by metabolons and hyperstructures on metabolic efficiency are unclear.
Thus, it seems that the strict maximization of metabolic efficiency is not the main factor determining the relative composition of the mixture of storage compounds accumulated after the sudden onset of nitrogen limitation.
Significantly different metabolic energy efficiency was also examined using the permutation test.
Through fever prevention, both oxygen utilization and caloric expenditure are reduced, so metabolic efficiency can be maximized [ 1].
No process for converting chemical energy to mechanical work is 100% efficient, and for a small animal this metabolic efficiency may be as low as 2% (Girardier et al., 1995; Heglund et al., 1982; Taylor and Heglund, 1982), with the majority of wasted energy being lost as heat.
Dr. Rudolph Leibel, a researcher in metabolism and obesity at Rockefeller University in New York, says metabolic efficiency may be the reason for the original weight problem.
The metabolic stability theory of aging appeals to a mathematical model of aging to show that metabolic stability, that is the capacity of a regulatory network to maintain stable concentrations of ROS and other critical metabolites, characterizes this metabolic efficiency, and is the main determinant of senescence.
