Sentence examples for metabolic dysfunction resulting from inspiring English sources

It has potential application as a bedside tool in the acute care and treatment of patients having other forms of metabolic dysfunction resulting from poisoning or sepsis [31].

Signals from tumor epithelial cells initiated metabolic dysfunction resulting in increased ROS that directly affected tumor cells by enhancing their invasive and metastatic qualities.

It was induced by metabolic dysfunction resulted from complex crosstalk of inflammatory cytokines.

These metabolic dysfunctions result in a range of long-term effects known as "diabetic complications".

We then investigated whether mitochondrial dysfunction resulting from metabolic inhibitors, such as Rotenone (an inhibitor of electron transfer from complex I to ubiquinone) and Antimycin A (an inhibitor of complex III), causes impairment of insulin signaling in SK-Hep1 hepatocytes.

In the present study, we demonstrated that mitochondrial dysfunction resulting from genetic or metabolic inhibition provoked insulin resistance via a decrease in the expression of IRS-1.

T2D is a complicated metabolic disorder, characterized by insulin resistance and/or pancreatic β-cell dysfunction resulting from both genetic and environmental factors [ 2, 4, 5].

Adiposity is associated with adipocyte mitochondrial dysfunction, resulting in an increase in oxidative and inflammatory stress that contributes to insulin resistance, diabetes, and other chronic metabolic diseases.

There is evidence from animal models that exposure to maternal obesity in utero can lead to offspring adiposity and cardiovascular and metabolic dysfunction, which may result from developmentally programmed hyperphagia, physical inactivity, and altered adipocyte metabolism [ 12].

One of the key questions the researchers were interested in answering was whether restricting dietary sugars in children with metabolic syndrome would lead to the metabolic dysfunction resolving.

It is because lifestyle addressing not only risk factor modification or reduction, but addresses the fundamental biological mechanisms of inflammation and oxidative, altered gene expression resulting metabolic dysfunction at the root of chronic disease.