Sentence examples for metabolic dysfunction include from inspiring English sources

Comprehensive treatment methods for hyperandrogenism and glucose and lipid metabolic dysfunction include lifestyle modifications, diuretic medicines, insulin-sensitising and anticholesteremic agents and oral contraceptives (OC).

Additionally, alteration of the gut microbiome leads to changes in the bile-acid pool, which affects the farnesoid X receptor (FXR) nuclear antagonist involved in the regulation of bile acid, as well as lipid and glucose metabolism (Li et al., 2013), and could cause metabolic dysfunction, including obesity and insulin resistance.

Intriguingly, both lead to metabolic dysfunction including insulin resistance and type 2 diabetes.

Lastly, many of the complications of metabolic dysfunction including nephropathy, neuropathy, and cardiac dysfunction cannot be successfully replicated in single genetic mouse models of metabolic dysfunction or in high fat-fed rodents [ 18].

In the postpartum period, this should be followed by energetic attempts to prevent them progressing to frank obesity and related metabolic dysfunction, including the potentially devastating risks of diabetes and cardiovascular disease.

Recent evidence squarely positions prostatic diseases as sequelae of systemic metabolic dysfunction, including hyperinsulinemia, hyperglycemia and hypercholesterolemia; however, the underlying etiologies of such susceptibilities remain unknown largely because of the absence of a molecular understanding of the basic metabolic machinery governing prostatic function.

For instance, bioenergetic metabolism plays a pivotal role in the replication of viruses, and the targeting of metabolism by viral proteins can translate into clinical symptoms, best exemplified by chronic hepatitis C, which is characterized by metabolic dysfunction, including insulin resistance.

Metabolic syndrome is a cluster of metabolic dysfunctions, including central obesity, hypertension, glucose, and lipid abnormalities.

HAART may lead to increase in metabolic dysfunctions, including insulin resistance, diabetes, dyslipidemia, lipodystrophic and cardiovascular diseases, 6, 14– 16 hypercholesterolemia, low levels of high-density lipoprotein cholesterol (HDL-C), hypertriglyceridemia, lactic acidemia, and hypercoagulopathy.

Mechanisms linking EAT to coronary microvascular dysfunction include changes in the secretion of adipokines, which have been related to insulin resistance and a state of metabolic stress [ 37].

We report that the xav mutation causes a loss of ETFDH function and defective electron transfer, and that both xav and fibroblasts from a phenotypically severe MADD patient have similar metabolic defects and mitochondrial dysfunction, including altered energy metabolism, dysregulated ROS production and altered expression of genes critical for mitochondrial function.