Based on the developmental origins of the health and disease hypothesis or fetal programming (4), the intrauterine environment represents a time when changes in maternal metabolism may affect distant metabolic dysfunction in the offspring mediated through physiological and/or epigenetic mechanisms.
The purpose of this review is to (1) provide an overview of the intervention data on the impact of RT on glucose metabolism, and (2) to hypothesize about the potential role of RT to combat metabolic dysfunction in patients with T2D by describing possible cellular and molecular mechanisms.
Visceral adiposity, increased adipocyte lypolysis, and metabolic dysfunction in obese postmenopausal women Am J Physiol 1996 270: E727078.
Purpose: The purpose of the proposed research is to characterize age-related metabolic dysfunction in human female skeletal muscle.
Human cohort studies have demonstrated a role for systemic metabolic dysfunction in osteoarthritis (OA) pathogenesis in obese patients.
Selective modulation of the intestinal microbiota with prebiotics reduces intestinal permeability and endotoxin concentrations, inflammation, and metabolic dysfunction in rodents.
To determine the effect of cinnamon on menstrual cyclicity and metabolic dysfunction in women with polycystic ovary syndrome (PCOS).
We showed that DSG attenuated metabolic dysfunction in HF diet-fed mice, as evidenced by reduction of blood glucose level and improvement of glucose and insulin intolerance.
Their data indicate that accelerated MIBI clearance may be associated with myocardial metabolic dysfunction in ACS.
Down-regulated autophagy is involved in the development of hepatic metabolic dysfunction in GSD Ia; however, the role of autophagy in the renal pathology is unknown.
Mounting evidence suggests that lipid-induced metabolic dysfunction in skeletal muscle is mediated in large part by stress-activated serine kinases that interfere with insulin signal transduction.
