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The purpose of this study was to test the physiological role of MyD88 in the state of metabolic disease using MyD88-deficient mice.
The goal of this study was to conduct a comprehensive examination of the effects of developmental exposure to BPA on outcomes related to metabolic disease, using doses that ranged from 5 to 50 000 µg/kg/d.
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Despite the large number of epigenetic studies of obesity and metabolic diseases using animal models, there are few epigenetic studies of obesity in humans.
In Spain, the women had a higher probability of indulging in self-medication [ 30]; in Brazil, among first- and last-year students enrolled in healthcare and nonhealthcare programs; being male was a protection factor against self-medication [ 19] and women with endocrinopathies and metabolic diseases used more dietary supplements [ 24].
This Perspective discusses experimental design and interpretation in studies addressing the mechanisms of sex differences in metabolic homeostasis and disease, using animal models and cells.
Recently, Shah et al. (2010) characterized the metabolic profile of patients with cardiovascular disease using 69 metabolites [ 49].
Patients with ASA score of III or more and severe metabolic, renal, or hepatic diseases, using cigarettes or antioxidant agents, were excluded from the study.
Because of the pivotal role that diet plays in causing metabolic syndrome in humans, most metabolic disease animal models use diet as a way to precipitate this syndrome.
In this Commentary, we discuss the progress of GWAS in identifying common disease loci for metabolic disease, and the use of the mouse as a model to confirm candidate genes and provide mechanistic insights.
The primary motivation for our study was to compare liver gene gene expression in hamster with humans and model organisms used in metabolic disease research.
Exhaled breath detection has been used to diagnose metabolic disease and monitor treatment for many years [ 7].
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