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updateKEGGPathway is used to build or update a local KEGG metabolic dataset for improving the efficiency of analysis and avoiding frequently repeated data downloads.
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Indeed, the metabolic dataset provides information about all coded proteins relevant for the microbial metabolism.
Finally, 63,620 individual metabolic reactions were retained as the metabolic reaction dataset for further study.
For demonstration purposes an exemplary workflow is executed with the Vanted framework, implementing the analysis of a comprehensive metabolic dataset taken from Sulpice et al.[ 53].
Two datasets were used to test these five algorithms, GDS1620 and metabolic pathway dataset for A. thaliana.
FluxMap and the underlying Vanted system provide a framework for the integration of comprehensive metabolic datasets and their combined representation in the network context.
In CA, metabolic datasets are decomposed into extreme trends representing elementary components of metabolic polymorphism called metabotypes.
To demonstrate that PathWave's extension of pathway analysis to the identification of significantly dysregulated subnetworks is more sensitive than common gene set enrichment approaches, we applied GSEA [ 9] and DAVID [ 10] to the same dataset for metabolic KEGG pathways.
We explore this by making use of an existing metabolic rate and mtDNA (cox1) dataset for the insect-like (arthropod) springtail Cryptopygus antarcticus travei Déharveng, 1981 (Collembola, Isotomidae) from sub-Antarctic Marion Island.
An assessment of glucose metabolism should be included in any future randomized controlled trials of antidepressants with a minimum dataset for reporting adverse metabolic consequences of treatment.
In order to compile a suitable reference dataset for the recently introduced 'Metabolic Quotient' (MQ, see below), further data, for which metabolic strain or stress (but at TVA/TIC < 0.7!) was assigned, were removed and transferred to the tester datasets.
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