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Strict metabolic control during the 1st year of type 1 diabetes is thought to be a key factor for achieving clinical remission.
In addition to the regulation of metabolic control during acute injury, exercise training is also a clinically relevant mechanism for ameliorating pathologies associated with metabolic syndrome.
Combining metabolomics, transcriptomic and proteomic data highlighted several aspects of metabolic control during ripening.
This may ultimately be shown to be the most important aspect of metabolic control during pregnancy.
Supplementary Tables 1 and 2 provide detailed information about comparison of severe hypoglycemia in the two periods and patients' metabolic control during the period 2007 2010.
This is a remarkable finding, because it shows that metabolic regulators are directly involved in EC phenotype decisions, demonstrating an unprecedented degree of metabolic control during angiogenesis.
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Several factors potentially deteriorate glycemic control in type 1 diabetic mothers after delivery: less incentive to achieve good metabolic control compared with during pregnancy, duties associated with childcare, and fear of hypoglycemic episodes during childcare.
Nonetheless, both interventions resulted in minimal deterioration in metabolic control over months during the transition period to adolescence.
A marked improvement of metabolic control was already apparent during periods with suboptimal graft function (Fig. 2 ).
The mean number of measurements among our study participants was 1.8 per patient per year, as some patients dropped out upon reaching the age of 18 years and some were evaluated only as inpatients during scheduled metabolic control assessment.
Thus, it can be hypothesized that better metabolic control, in general and specifically during acute ischemic syndromes, may induce a more efficient stimulation of EPC-mediated neovascularization in ischemic tissue, thus reducing residual ischemia.
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