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Both of these metabolic changes result from oncogene mutations with the tumour cells, most notably the p53 gene-mutation, which occurs commonly in lung cancer.
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Antipsychotic drugs can also have severe physical side effects, causing drastic weight gain and metabolic changes resulting in lifelong physical problems.
Pollutants' stresses might have induced metabolic changes resulting in the increased utility of stored carbohydrates as an energy source.
Transcriptional and metabolic changes resulting from the improvement of galactose utilization were found maintained during growth on glucose.
Cell stress occurring under ischemia or/and inflammation always present in ICU patients compromise mitochondrial function, which contributes greatly to the metabolic changes, resulting in cell dysfunction and death, which in turn cause organ failure.
This study was designed to explore the metabolic changes resulting from catch-up growth in adult (CUGA) induced by varying degrees of nutrition promotion after undernutrition and to confirm whether these changes are transient or not.
In this study, the subtle metabolic changes resulting from diclofenac treatment could only be determined using an OGTT time course.
This first exploratory study shows that subtle metabolic changes resulting from an anti-inflammatory treatment could only be determined using a metabolic perturbation test in a well-designed clinical study using metabolic profiling analysis.
As an effort to understand underlying mechanism(s) for the inhibition by the mitochondrial antagonists of the pMV-absorption by 2C T cells, we first examined metabolic changes resulting from the drug treatments.
The systems biology approach applied in this study provides a coherent picture of metabolic changes resulting from impaired STAT5 signalling by the growth hormone receptor, and supports a potentially important role for taurine in enhancing β-oxidation.
The metabolic changes resulting from the induction of cell death should result in an inhibition of lipid biosynthesis.
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