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Biological fluids as blood/serum/plasma, urine, saliva, tear and cerebrospinal fluid, due to their accessibility, offer ease of collection with minimal or no discomfort to the patient and provide a ready footprint of the metabolic changes occurring during disease.
Regardless, the metabolic changes occurring in the livers of Eps8KO mice closely resemble those occurring under condition of CR.
Ultimately, direct analysis of cells/tissues is a more straightforward way to understand the actual disease-associated metabolic changes occurring.
To further address the metabolic changes occurring in the absence of myogenin, wild-type and Myog-deleted mice were run under the high-intensity regimen while measuring their oxygen consumption and carbon dioxide production.
MRS was used to identify the metabolic changes occurring following Fas-induced apoptosis.
The Warburg effect is an important concept for understanding metabolic changes occurring in innate immune cells upon activation.
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This study was designed to determine whether these metabolic changes occur with short-term oral oestrogen in premenopausal women.
Both crowding and live-chilling before slaughter significantly affected rigor mortis, pH and muscle glycogen indicating that muscle metabolic changes occurred post-slaughter.
These studies, including our own work, indicate that under these experimental conditions Arabidopsis cold acclimates, metabolic changes occur and the expression of clock components is disrupted.
Laboratory studies show that seasonal metabolic changes occur in ring-tailed lemurs and brown lemurs [36], [58], with variations in hair metabolism, levels of subcutaneous fat deposition, and body weight, among various physiological criteria.
In experimental sepsis, colonic metabolic changes occur prior to changes in small intestine or stomach [ 4].
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