Sentence examples for metabolic changes measured from inspiring English sources

Metabolic changes measured by PET have been shown to be more sensitive in detecting response early in the course of chemotherapy as compared with both conventional imaging techniques (EUS and CT) and endoscopy [ 11].

Changes in the promoter methylation status of cancer-related genes isolated from cfDNA may also be observed along with tumor metabolic changes measured by FCH PET/CT that appear to correlate with changes in cfDNA content.

The study also aims to validate the predictive role of early tumor metabolic changes measured by positron emission tomography (PET) scan (both phase I and II) and to assess the diagnostic accuracy of pre-surgical rectal biopsy, performed after the induction of anaesthesia in all surgical operations and analysed by intraoperative pathology (both phase I and II).

Furthermore, the identification of biomarkers predictive of pathologic tumor regression, including early tumor metabolic changes measured by 18FDG-PET/TC, could improve the selection of patients candidate to a conservative surgical approach, which represent a major goal, considering the morbidity of total mesorectal excision and its impact on patients quality of life and costs.

Therefore, this work should be considered a pilot study, and the reliability of cerebral metabolic changes measured by MD for diagnosis or prediction of BM in patients with SAH will have to be confirmed prospectively in a substantially larger study population.

We will also evaluate mechanistically-based pharmacokinetic/pharmacodynamic biomarkers on tumor and blood samples and the predictive role of early (within 11 days after the beginning of SCRT) tumor metabolic changes measured by 18FDG-PET/TC in patients undergoing phase II trial.

Therefore, more comprehensive experiments monitoring behavioural traits in combination with metabolic changes to measure differences in fuel oxidation will be needed to provide a better basis for future quantitative evaluations of energy expenditure components and fuel utilisation.

Many of these high-throughput experiments directly or indirectly measure metabolic changes within a cell, for example microarrays indirectly measure enzyme concentration and metabolomics experiments directly measure changing metabolite concentrations.

The changes observed for steady-state mRNA levels in the different conditions were compared with the measured metabolic changes (Additional file 5: Figure S3).

We used a measure of total leisure time sitting in the present study, which may provide better insight into overall effects of sitting on adverse metabolic change than measures which are context-specific.

The present manuscript focused on functional and metabolic changes but does not measure perfusion or steatosis, two mediators of metabolism and function, due to the duration of MRI scans and tolerability by patients.