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However, the results from a variety of animal models of diabetes and obesity are ambiguous in terms of cardiac function and the contribution of metabolic changes concerning substrate utilization and hyperglycemia on the one hand, and adipose tissue-derived inflammation on the other, for the myocardial phenotype observed [ 2, 37, 158].
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In view of side effects associated with the atypical neuroleptics such as weight gain and metabolic changes [ 48], serious concerns regarding their long-term use remain.
Cost and potential side effects (metabolic changes, carpal tunnel syndrome, and anemia) raise concerns about its use.
Although early studies suggest a range of activation of other genes in a variety of other tissues, where these have been identified, they are mainly concerned with metabolic effects and can be regarded either as secondary to the profound metabolic changes or as primary and consistent with regulation of lipid metabolism through the PPARs.
We were concerned that this short-term ketogenic feeding paradigm might trigger secondary metabolic changes such as hyperglycemia or dyslipidemia that could confound subsequent analysis.
One hypothesis is that something about the composition of breast milk may set off metabolic changes or somehow program the child's metabolism.
Metabolic changes accompany the degeneration.
The experience, with the metabolic changes it sets off, is a simulacrum of dying.
Scientists are looking closely at immunizations, infections, metabolic changes and environmental factors.
Those taking molindone gained less than a pound, on average, and had little metabolic changes.
It doesn't account for metabolic changes that happen when people change diet," said Kevin Hall, who led the research.
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