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We identified and quantified (i) metabolic differences between genetically engineered human cell lines, (ii) alterations in cellular metabolism induced by differentiation of mouse myoblasts into myotubes, and (iii) metabolic changes caused by activation of neurotransmitter receptors in mouse myoblasts.
Metabolic changes caused by all possible sets of triple reaction knockouts were evaluated using a reduced metabolic model, which was constructed to significantly reduce the computational cost.
The overall metabolic changes caused by cranberry juice or apple juice consumption using a global 1H NMR-based metabolomics approach were investigated.
The analysis from transcription level conducted in this study is of great importance for further investigation of metabolic changes caused by ARTP mutagenesis.
These changes are probably due to metabolic changes caused by the illness per se but not to malnutrition.
These results were further evaluated by the VO2 test, to investigate the metabolic changes caused by GPR91 deletion.
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Here, we asked what metabolic changes cause the reduced adiposity and resistance to obesity in Mstn−/− mice.
High level of physical demand during these events induces a wide range of metabolic changes, causes micro-injuries to the muscles and other tissues, which increases migration of white blood cells to the sites of injury, and induces acute phase inflammatory reactions (Kim et al. 2007; Tidball 2005; Bessa et al. 2008).
In this study, a urine metabonomic method based on gas chromatography coupled with mass spectrometry (GC/MS) was employed to study the protective efficacy and metabolic profile changes caused by YGJD in carbon tetrachloride (CCl4 -induced liver fibrosis.
Comprehensive literature reviews reported that a stress-migraine interaction was hypothesized because of the physiological stress response involved in neuroendocrine, metabolic, and immune changes caused by the activation of the hypothalamic-pituitary-adrenocortical axis, and of the sympathetic nervous system [22 24].
The metabolic changes are caused by the insufficiency of secretion or action of endogenous insulin [1].
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