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The extensive repertoire of genes (Table 5) encoding proteins involved in signal transduction in L. biflexa (287 CDS) compared with L. interrogans (214 CDS) and L. borgpetersenii (167 CDS) is consistent with an enhanced metabolic capability in L. biflexa reflected by its environmental habitat and likely contributes to its enhanced growth rate relative to the pathogens.
Apicomplexan parasites differ drastically from each other in their metabolic functions, and have a significantly reduced metabolic capability in comparison to the chromerids.
Like the origin of PAH-MN discussed above, the same strength of natural selection minimizing toxic side effects might also have restricted the abandonment trajectories in the evolutionary process for disuse of the dispensable metabolic capability in the host-dependent mycobacteria.
Urinary metabolites are often used in preference to the parent compound in blood because urine collection is less invasive; however, differences in urine metabolite levels can represent individual differences in metabolic capability in addition to differences in exposure, again leading to exposure misclassification if the biomarker is not the biologically active agent.
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Xie et al. (2011) also reported similar common metabolic capabilities in five different AMDs from Cu mines.
The presence of such degradative metabolic capabilities in the organisms cultured from our samples may partially be explained by the disposal of organic solvents, such as kerosene-based solvents (from the "solvent extraction process") into the heaps.
Metagenomics is a powerful approach to screening microbial diversity and metabolic capabilities in any environment.
Concentration data indicate that the age dependency was due to lower metabolic capabilities in the young rats (Sheets et al. 1994).
Subsequently, we decided to focus the remainder of the study on modelA, as it captures most of the known metabolic capabilities in the mouse.
While they do not allow the analysis of non-equilibrium dynamics, stoichiometric models have been found very useful for predicting the metabolic capabilities in steady state [ 12- 15].
Unlike most other chemicals, as a naturally occurring endogenous compound with substantial concentrations in the blood and all tissues and with prodigious metabolic capabilities in the nasal epithelium and upper respiratory tract, formaldehyde must be considered differently.
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