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Could we assess the pharmacokinetic and metabolic behavior of Ga -and In-labeled compounds administered simultaneously?
The goal of this study was to assess the potential of HPLC-ICP-MS to characterize the metabolic behavior of imaging probes.
Hemodynamic, respiratory, and metabolic behavior of the animals during the PaCO2 equilibrium phase is shown in Additional file 3: Table S2.
Impedimetric SM7 measurements were performed in the Quantibac instrument that can be employed to evaluate the metabolic behavior of microorganisms in different culture media using two fixed frequencies.
These studies failed to capture the enhanced glycemic production and reduced renal and hepatic clearances, the balance of which can dominate the overall metabolic behavior of the critically ill.
Indeed, despite a recent proteomic study describing the influence of lignin in the metabolic behavior of C. acetobutylicum ATCC 824 with cellobiose as the substrate (Raut et al. 2016), the capability of Clostridium strains to ferment mixtures of cellobiose and glucose in synthetic medium is not well studied yet.
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However, new studies highlight the impact of metabolic behavior on the maintenance and function of intestinal stem cells and hair follicle stem cells.
Both FBA and dFBA (via SOA approach) can be done in MicrobesFlux to simulate the metabolic behaviors of organisms in metabolic steady state and dynamic state.
These differential metabolic behaviors of the three colorectal cell lines show how important an adequate knowledge of the "metabolic remodeling" that follows a given cancer treatment is towards the correct (re design of therapeutic strategies against cancer.
If, on the other hand, data and model are compatible, the new evidence may still narrow down the set of possible metabolic behaviors of the cell, thus enriching the model (Covert et al., 2004).
The red lines in Figure 6 (andand b1) indicate that the simulated concentrations of threonine (X26) and lysine (X93) agreed with the metabolic behaviors of experimental data obtained by metabolome analysis with significant correlations (p-values < 0.005; detailed in Supplementary Model - additional file 2).
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