Evidence for an effect of APOE on brain function in healthy individuals is reinforced by studies using metabolic and functional brain imaging techniques [ 20- 22] and reaction time based attention tasks [ 23, 24].
Taken together these data suggest that an impairment in Akt signaling might be related to the development of age-related metabolic and functional disorders in skeletal muscle and importantly, that the re-establishment of Akt functionality may be a useful strategy for diminishing the deleterious effects of aging on muscle structure and function.
Such a phenonmenon would be another example of the metabolic and functional complexity of the nervous system.
Metabolic and functional imaging 8.
Last, the hearts subjected to retrograde cardioplegia or antegrade cardioplegia showed similar and complete metabolic and functional recovery during reperfusion.
The development of new imaging techniques such as molecular, metabolic and functional imaging has paralleled the expanding knowledge on tumour biology.
Physiological and genomic data show that each strain has different metabolic and functional traits that may reflect contrasting modes of life (Bayer et al. 2016).
Malnutrition represents a continuous spectrum ranging from marginal nutrient status to severe metabolic and functional alterations and this in turn, affects clinical outcome.
Literature suggests that sustained inflammation is the driving force behind these metabolic and functional changes during the recovery from sepsis [9].
This process focuses on using the natural self-organising properties of cells in order to produce a functional tissue which has measurable: mechanical, metabolic and functional properties.
Assessment of muscle wasting in COPD is relevant as it is independently associated with metabolic and functional consequences and even survival.
