Sentence examples for metabolic alterations regulated from inspiring English sources

These data support the idea that FGF21 is an independent indicator of genetic hepatocarcinogenesis. p53 may account for an additional or combinatory mechanism for regulating FGF21 expression in association with liver damage and carcinogenesis beyond metabolic alterations regulated by several nuclear receptors (NRs).

One of the key goals is to delineate how metabolic alterations of cancer influence metabolism-regulated function and differentiation of tumor resident T cells and how such effects might be altered by immunotherapy.

Epigenetic and genomic alterations regulate the transcriptional landscape of cells during cancer onset and progression.

Insulin resistance results in numerous metabolic abnormalities in addition to increased NEFA concentrations and hyperinsulinemia that were modelled in isolation in this study, therefore further in vitro studies will be required to understand how the complex metabolic alterations of insulin resistance regulate inflammation in human monocytes.

Given its central role as a tumor suppressor, it is not surprising that p53 can regulate several aspects of cellular metabolism and thereby counteract many of the metabolic alterations associated with cancer development .

This suggests that these psychotropic drugs target central nervous system neurons that also regulate mechanisms controlling energy balance and associated metabolic alterations.

Once activated, NF-κB regulates the expression of multiple inflammatory mediators, including IL-6, TNF-α and other factors implicated in the metabolic alterations.

Studying cultured cells, we previously reported that hypoxia up-regulated the HIF-α-dependent microRNA-210 (miR-210), leading to specific mitochondrial and metabolic alterations (Chan et al, 2009).

Sepsis is accompanied by severe metabolic alterations.

Cancers exhibit thermodynamic and metabolic alterations and abnormal CRs.

Our results demonstrate that levosimendan improves Cellular metabolic alterations.