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"metabolic adaptation" is correct and usable in written English.
You can use it to refer to the ability of an organism to adjust to different conditions and environments in order to survive and reproduce. For example: "Certain species of frogs have adapted to their environment by undergoing metabolic adaptations to survive in warmer climates."
Exact(60)
Metabolic adaptation of cancer cells extends beyond ATP production.
Cancer cells undergo metabolic adaptation and thereby gain selective survival and growth advantage (Fig. 1).
Another study addressed metabolic adaptation of P. aeruginosa during chronic CF lung infection [25].
Accumulation of certain organic solutes (known as osmoprotectants) is a common metabolic adaptation found in diverse plant species.
In another metabolic adaptation, antioxidant species scavenge ROS to protect rice plants against oxidative damage induced by cold stress.
Accumulation of certain organic solutes (known as osmoprotectants) is a common metabolic adaptation found in diverse taxa.
Further advances unravelled how some prototypical PRRs get activated to initiate metabolic adaptation and defence responses that stop invaders.
During septic shock, the Th pattern of T lymphocytes shifts, which can be regarded as a metabolic adaptation as it is mediated in part by adrenergic stimulation [8].
In another study, Mauro et al. showed that NF-κB plays a role in metabolic adaptation in cancer by upregulating OXPHOS [114].
Improved mitochondrial function associated with mitohormesis or metabolic adaptation can attenuate the impact of mitochondrial diseases, aging as well as age-related metabolic and neurodegenerative disorders.
Interestingly, MYC promotes the metabolic adaptation of tumor cells [109] by activating genes important for mitochondrial biogenesis and function [110, 111].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com