HERMANN--Meta, age 98, (nee Chesney), beloved wife of the late Hans Hermann, died peacefully in her sleep on April 26th.
Prior to this IPD meta-analysis age was thought to modify the effects of amoxicillin.
Correlations between metacognitive efficiency (meta-d′/d′), age and neuropsychological measures were computed using Pearson's product-moment correlations implemented in R 3.0.1.
Of the 16 risk factors identified in our systematic review and meta-analysis, age, current smoking, cataract surgery, and potentially family history were strongly and consistently associated with late AMD.
The range of ages included in a study is likely to influence the results – a wide range likely leading to more pronounced effects: in this meta-analysis age range was not considered due the variability of the studies designs and to the lack of information presented in the articles.
Second, samples of sexually dysfunctional men were, on average, older than the sexually functional men and, in our meta-analysis, age was positively related to concordance among men, which would have reduced the possibility of observing a difference between the two groups.
The combined pre and peri trauma risk factors highlighted in previous meta-analyses, age, gender, level exposure, exposure characteristics (see Table 3) and perceived life threat at the time, account for 20% of the variance (adjusted R-squared) in PDS scores.
We confirmed that the effect sizes and Manhattan plot in the meta-analysis were almost identical to those in the meta-analysis using age and sex as covariates (Additional files 4 and 5).
In meta-regression analyses, age was found to exert a significant influence on the association between rs10811661 and type 2 diabetes (P = 0.003), as well as between rs7754840 and gender (P = 0.034).
Moreover, we performed meta-regression with age as covariate to test for an age-effect, but there were no significant indications of this being the case.
To explore the influence of case mix, we evaluated 2 baseline variables in separate meta-regressions: mean age and mean baseline arterial partial pressure of oxygen/fractional concentration of inspired oxygen ratio (PaO2/FiO2).
