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RAS: carried out PCR analyses of met expression, and provided comments on the manuscript draft.
The restoration of MET expression was confirmed through immunoblot analysis.
Limited data exists on the relationship of MET expression and prognosis in ccRCC.
Conversely, downregulation of MET expression in tumor cells can lower their tumorigenic potential [24].
Met expression is also responsive to various types of stress, particularly low oxygen tension or hypoxia [22].
Interobserver variation was 8% for Met expression.
Similar(23)
In biodistribution studies, uptake in MKN-45 (human gastric carcinoma with high c-MET expression) tumors of 76Br-onartuzumab was about 2-fold higher than in U87-MG tumors (moderate level c-MET expression).
Then the authors tested 11C-SU11274 as a micro-PET imaging agent for c-MET expression in vivo.
Thus, the development of more effective noninvasive detection methods for accessing c-MET expression and activation is needed.
Conversely, prenatal Tpr-Met expression was lethal after birth.
We have developed a proximity assay for quantification of total c-MET expression in FFPE specimens.
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